Microwave Assisted Synthesis of Some Quinoxaline Derivatives

نویسندگان

  • AMIT DWIVEDI
  • ANSHU SINGH
  • ANIL MISHRA
چکیده

The high commercial demand for quinoxalines needs a rapid, greener and safer synthetic method among the chemists. A series of quinoxaline derivatives has been synthesized by condensation of diamines and dicarboniles in microwave heating conditions and in solvent free media. This environmentally benign synthetic approach gives us excellent yields (80-90%) in shorter reaction time (3.5 minutes.). The method is cleaner with an easier work-up process. The structures of these synthesized products are based on elemental analysis and mass spectral data.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Microwave-Assisted Three Component Cyclocondensation Reaction: A Facile Synthesis of Highly Functionalized Cyclohexene Derivatives

Microwave-assisted three component cyclocondensation reactions of aldehydes, amides and dienophiles in the presence of acetic anhydride and para-toluenesulfonic acid as a catalyst to afford the highly substituted cyclohexene derivatives, in relatively good yields after several minutes are reported.

متن کامل

Microwave Assisted Multi-component Synthesis of 4Hchromene Derivatives by Nano-coconut Shell-BF3 as a New Heterogeneous Catalyst

Microwave assisted reactions have gained considerable attention, due to versatility and reduction ofsolvent and reaction time. The reaction of a nano-coconut shell and boron tri-fluoride in diethylether solvent resulted in preparation of nano-coconut shell-BF3 as a catalyst. The nano-coconutshell-BF3 catalyst has been characterized by fourier transform infrared spectroscopy (F...

متن کامل

Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation

An efficient and practical protocol has been developed to synthesize 5,6-dihydroindolo[1,2-a]quinoxaline derivatives by CuI-catalyzed intramolecular N-arylation under microwave irradiation. This method rapidly afforded the tetracyclic products with good to excellent yields (83-97%) in short reaction times (45-60 min).

متن کامل

Microwave-assisted Synthesis of Nـ alkyl 2ـ ketomethyl quinoline Derivatives Under Solvent-free Conditions

A series of Nـ alkyl 2ـ ketomethylquinoline derivatives were synthesis by reaction of benzoyl chloride derivatives with Nـ methyl quinaldine iodide in the presence of triethyl amine under microwave irradiation. Enaminone form of the product study by spectroscopy method. The result revealed the  Nـ alkyl 2ـ ketomethylquinoline the fixed enaminone tautomer.

متن کامل

Microwave-assisted solvent-free synthesis and in vitro antibacterial screening of quinoxalines and pyrido[2, 3b]pyrazines.

We report herein the microwave assisted synthesis, without solvents and catalysts, of 6-substituted quinoxalines and 7-substituted pyrido[2,3b]pyrazines. The compounds were obtained in good yields and short reaction times using the mentioned procedure and two new structures are reported. A complete ¹H- and ¹³C-NMR assignment was performed using 1D and 2D-NMR. Additionally, an in vitro screening...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2013